From Feasibility Bottlenecks to Instant Insight: How McKesson Compile Is Redefining RWD Accessibility with Datavant Connect

In the high-stakes world of life sciences, where timelines are tight and data-driven decisions shape the success of therapies, time to insight can mean the difference between momentum and missed opportunity.

For McKesson Compile, a leading healthcare data provider known for its analytics-ready, high-capture datasets, this reality made it a natural fit to join Datavant’s Lighthouse Partner program—an initiative to accelerate the creation and adoption of a next-generation, cloud-first data discovery and assessment platform.

Now live with Datavant Connect powered by AWS Clean Rooms, McKesson Compile is transforming how life sciences teams discover, evaluate, and engage with real-world data (RWD). The result: faster feasibility, lower overhead, and more meaningful commercial conversations.

Why McKesson Compile Is Choosing a Cloud-First Approach

When evaluating potential data partners, biopharma teams often find themselves stuck in prolonged back-and-forth cycles to get baseline feasibility estimates. McKesson Compile is leveraging Datavant Connect powered by AWS Clean Rooms to eliminate that friction. Enabling real-time, self-service queries of McKesson Compile’s analytics-ready data will help teams move from question to insight in hours, not weeks.

The decision to participate was driven by a clear need to modernize data profiling and feasibility assessments. Unlike legacy token-based overlaps that often require custom extracts and multi-week turnaround times, the new cloud-native approach allows prospective buyers to generate real-time patient counts across multiple variables such as disease area, age cohort, and timeframe without manual intervention. For RWE (real-world evidence) and clinical analytics teams, this time savings is a game changer.

Datavant Connect powered by AWS Clean Rooms: Built for Collaboration

Datavant Connect powered by AWS Clean Rooms brings a secure, scalable, and cloud-first approach to RWD discovery that benefits both data producers and data consumers. Here's how it works:

• Live Connection to Native AWS Environment: Data aggregators like McKesson Compile register their data on Datavant Connect through AWS using a glue database and glue table that points to their S3 storage. This creates a live connection between the natively stored dataset and Datavant Connect (the interface where potential buyers can explore available data) – no data duplication or data movement required.
  
  
• No Underlying Data Movement: Through AWS Clean Rooms, queries are run in a secure, neutral space, allowing data consumers to evaluate the data without transferring sensitive information. Data producers maintain full control over access, with granular governance capabilities.
  
  
• Scalable Data Discovery: Buyers can simultaneously evaluate multiple datasets, leveraging deeper queries to build custom cohorts, and gain a standardized view of coverage and capture rate metrics—all from a single interface.
  
  

For McKesson Compile, this architecture doesn’t just streamline discovery, it unlocks a more strategic role in the buyer’s workflow.

Driving Commercial Impact Through Early Workflow Integration

McKesson Compile’s adoption of Datavant Connect powered by AWS Clean Rooms is a commercial accelerant.

With Datavant Connect, McKesson Compile becomes part of the first step in the journey for buyers seeking self-serve data discovery options, embedding its analytics-ready data directly into the feasibility and planning process. This early integration empowers life sciences teams to make informed decisions faster through self-serve feasibility queries and cohort insights – helping them validate data coverage and accelerate planning. At the same time, it provides McKesson Compile a new channel to uncover business opportunities by putting the data in front of qualified teams actively seeking solutions.

It also reduces the manual lift for McKesson Compile’s internal teams. By enabling buyers to independently explore data fit, Datavant Connect minimizes redundant Q&A cycles and accelerates commercial conversations, helping buyers make faster, more confident data purchasing decisions.

McKesson Compile: A Data Asset Built for Real-World Decision-Making

McKesson Compile’s data products are designed for immediacy, accuracy, and action. Provider 360 ReadyData™ includes detailed and current reference and affiliation data on U.S. healthcare providers (HCPs) and organizations (HCOs) while Patient ReadyData is a collection of real-world datasets that contain anonymized patient-level data in the form of open and closed medical and pharmacy claims from commercial payers, Medicare, and Medicaid.

With deep expertise in patient claims datasets and provider relationships, McKesson Compile delivers high-fidelity, normalized, and deduplicated data that’s provisioned within 48 hours. Highlights of the McKesson Compile offering include:

• Analytics-Ready Structure: Out-of-the-box usability eliminates hours of data wrangling.
  
  
• Premium Service Model: A customer-first ethos that supports tailored implementations and continuous improvement.
  
  
• Speed: Fast provisioning, seamless integration, and ongoing product enhancements—at no extra cost.
  
  

In short, McKesson Compile helps life sciences companies move faster, smarter, and with more confidence as they bring new therapies to market.

Impact for Life Sciences Teams

For life sciences clinical, commercial, and Health Economics and Outcomes Research (HEOR) teams, the benefits are immediate and tangible:

• Instant Feasibility Estimates: No more delays or dependency on vendor-led extracts—get patient counts in real time.
  
  
• Multi-Dataset Comparison: Evaluate multiple RWD sources side-by-side to identify incremental data contributions.
  
  
• Smarter Decisions, Sooner: Streamline planning, focus vendor engagement, and accelerate internal buy-in.
  
  

In a landscape where speed, transparency, and control are increasingly non-negotiable, Datavant Connect delivers with strong partners like McKesson Compile.

The Bigger Picture: A More Connected RWD Ecosystem

As the healthcare data ecosystem matures, interoperability and collaboration will define the next wave of innovation. By embracing Datavant Connect powered by AWS Clean Rooms, McKesson Compile isn’t just enhancing its data delivery model—it’s helping redefine how life sciences teams access and evaluate data across the board.

Together, we’re building a more connected, efficient, and insight-rich future for real-world data.

Ready to move faster from feasibility to insight?

Learn more about McKesson Compile’s analytics-ready data and how it fits into your discovery workflow by connecting with the team here.

 Plus, the McKesson Compile team will be at Fierce Pharma Week in Philadelphia! Find the team at Booth #421 from Sept 9 - 11.